“The Miami Framework for ALS and related neurodegenerative disorders: an integrated view of phenotype and biology”

Manuscript emanating from the 2nd International Pre-Symptomatic ALS Workshop (Feb 2023).

A unifying conceptual framework for:

• defining ALS and related disorders based on biology rather than clinical phenotype
• understanding the spectral relationship between ALS, FTD and other neurodegenerative disorders
• the clinical continuum of disease – from clinically silent, through prodoromal, to clinically manifest stage

Podcast: