Based on data from the CReATe Consortium’s Phenotype-Genotype-Biomarker (PGB1) natural history study.
We found a lower frequency of cognitive and behavioral impairment in ALS than previously reported, with impairment and decline in only a small subset.
The cognitive dysfunction observed were not fully explained by gene mutations (e.g. C9orf72 repeat expansion) associated with FTD.
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