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Verdiperstat in Amyotrophic Lateral Sclerosis: Results From the Randomized HEALEY ALS Platform Trial.

by Alexandra Grace | Dec 19, 2025

Writing Committee for the HEALEY ALS Platform Trial; Andrews J, Paganoni S, Macklin EA, Chibnik LB, Quintana M, Saville BR, Detry MA, Vestrucci M, Marion J, McGlothlin A, Young E, Chase M, Pothier L, Harkey B, Yu H, Sherman A, Shefner J, Hall M, Kittle G, Connolly MR,...

Efficacy and safety of zilucoplan in amyotrophic lateral sclerosis: a randomized clinical trial.

by Alexandra Grace | Dec 19, 2025

Paganoni S, Fournier CN, Macklin EA, Chibnik LB, Quintana M, Saville BR, Detry MA, Vestrucci M, Marion J, McGlothlin A, Ajroud-Driss S, Chase M, Pothier L, Harkey BA, Yu H, Sherman AV, Shefner JM, Hall M, Kittle G, Berry JD, Babu S, Andrews J, Dagostino D, Tustison E,...

An observational study of pleiotropy and penetrance of amyotrophic lateral sclerosis associated with CAG-repeat expansion of ATXN2.

by Alexandra Grace | Dec 19, 2025

Demaegd KC, Kernan A, Cooper-Knock J, van Vugt JJFA, Harvey C, Moll T, O’Brien D, Gornall S, Drury L, Farhan SMK, Dion PA, Rouleau GA, Western A, Parsons PJ, Mclean B, Benatar M, van den Berg LH, Van Damme P, Willem Dankbaar J, Hendrikse J, Koole W, de Bie C,...

Reply: Overstating harms can have consequences.

by Alexandra Grace | Dec 19, 2025

Benatar M, McDermott C, Turner MR, van Eijk RPA. Reply: Overstating harms can have consequences. Brain. 2025 Jun 3;148(6):e54. Epub 2025 Feb 5. [PubMed link]

Amyotrophic lateral sclerosis caused by SOD1 variants: from genetic discovery to disease prevention.

by Alexandra Grace | Dec 19, 2025

Benatar M, Robertson J, Andersen PM. Amyotrophic lateral sclerosis caused by SOD1 variants: from genetic discovery to disease prevention. Lancet Neurol. 2025 Jan;24(1):77-86. [PubMed link]
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