Research Studies

Study Title

Lost in translation: Treatment Trials in the SOD1 Mouse and in Human ALS

Enrollment Status

Completed

Principal Investigators

Michael Benatar, MD, PhD

Study Type

Other

Goals

Enrolling

Eligibility

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Study Involvement

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Contact

Links

Primary Funding Source

Related Publications

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Benatar M, Wuu J, Andersen PM, Atassi N, David W, Cudkowicz M, Schoenfeld D. Randomized, double-blind, placebo-controlled trial of arimoclomol in rapidly progressive SOD1 ALS. Neurology. 2018 Feb 13;90(7):e565-e574. Epub 2018 Jan 24.

https://pubmed.ncbi.nlm.nih.gov/29367439

Schnabel J. Neuroscience: Standard model. Nature. 2008 Aug 7;454(7205):682-5.

https://pubmed.ncbi.nlm.nih.gov/18685674

Benatar M. Lost in translation: treatment trials in the SOD1 mouse and in human ALS. Neurobiol Dis. 2007 Apr;26(1):1-13. Epub 2007 Jan 3.

https://pubmed.ncbi.nlm.nih.gov/17300945

Related Presentations & Lectures

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Benatar M (presenter), Wuu J, Atassi N, Cudkowicz M, Schoenfeld D. Randomized, phase II trial of arimoclomol in rapidly progressive SOD1 ALS. Late-breaking session platform presentation at the 27th International Symposium on ALS/MND, Dublin, Ireland, Dec 7-9, 2016.

Flinders University Center for Neuroscience Seminar. Adelaide, Australia, September 2015.

Benatar M (invited speaker). Challenges and Opportunities in ALS Therapy Development. Congress on Motor and Cognitive Degenerative Diseases. Yachay, Ecuador, January 2015.

Benatar M (invited speaker). ALS Therapy Development: Challenges and Opportunities. ALS Association Wisconsin Chapter. Milwaukee, WI, May 2014.

Benatar M (invited speaker). Predictive, Preventive and Therapeutic Studies in Familial ALS. ALS Association Annual Leadership Forum. Orange County, CA, January 2008.